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A human kinase yeast array for the identification of kinases modulating phosphorylation‐dependent protein–protein interactions

Protein kinases play an important role in cellular signaling pathways and their dysregulation leads to multiple diseases, making kinases prime drug targets. While more than 500 human protein kinases are known to collectively mediate phosphorylation of over 290,000 S/T/Y sites, the activities have be...

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Detalles Bibliográficos
Autores principales: Jehle, Stefanie, Kunowska, Natalia, Benlasfer, Nouhad, Woodsmith, Jonathan, Weber, Gert, Wahl, Markus C, Stelzl, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883442/
https://www.ncbi.nlm.nih.gov/pubmed/35225431
http://dx.doi.org/10.15252/msb.202110820

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