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IKKα plays a major role in canonical NF-κB signalling in colorectal cells

Inhibitor of kappa B (IκB) kinase β (IKKβ) has long been viewed as the dominant IKK in the canonical nuclear factor-κB (NF-κB) signalling pathway, with IKKα being more important in non-canonical NF-κB activation. Here we have investigated the role of IKKα and IKKβ in canonical NF-κB activation in co...

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Detalles Bibliográficos
Autores principales:	Prescott, Jack A., Balmanno, Kathryn, Mitchell, Jennifer P., Okkenhaug, Hanneke, Cook, Simon J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2022
Materias:	Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883499/ https://www.ncbi.nlm.nih.gov/pubmed/35029639 http://dx.doi.org/10.1042/BCJ20210783

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