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Clonal evolution in chronic lymphocytic leukemia is scant in relapsed but accelerated in refractory cases after chemo(immune) therapy

Clonal evolution is involved in the progression of chronic lymphocytic leukemia (CLL). In order to link evolutionary patterns to different disease courses, we performed a long-term longitudinal mutation profiling study of CLL patients. Tracking somatic mutations and their changes in allele frequency...

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Detalles Bibliográficos
Autores principales:	Zapatka, Marc, Tausch, Eugen, Öztürk, Selcen, Yosifov, Deyan Yordanov, Seiffert, Martina, Zenz, Thorsten, Schneider, Christof, Bloehdorn, Johannes, Döhner, Hartmut, Mertens, Daniel, Lichter, Peter, Stilgenbauer, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883533/ https://www.ncbi.nlm.nih.gov/pubmed/33691380 http://dx.doi.org/10.3324/haematol.2020.265777

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