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Identification of a novel genetic locus associated with immune-mediated thrombotic thrombocytopenic purpura

Immune thrombotic thrombocytopenic purpura (iTTP) is an ultra-rare, life-threatening disorder, mediated through severe ADAMTS13 deficiency causing multi-system micro-thrombi formation, and has specific human leukocyte antigen associations. We undertook a large genome-wide association study to invest...

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Detalles Bibliográficos
Autores principales:	Stubbs, Matthew J., Coppo, Paul, Cheshire, Chris, Veyradier, Agnès, Dufek, Stephanie, Levine, Adam P., Thomas, Mari, Patel, Vaksha, Connolly, John O., Hubank, Michael, Benhamou, Ygal, Galicier, Lionel, Poullin, Pascale, Kleta, Robert, Gale, Daniel P., Stanescu, Horia, Scully, Marie A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883548/ https://www.ncbi.nlm.nih.gov/pubmed/33596643 http://dx.doi.org/10.3324/haematol.2020.274639

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