The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma

Multiple myeloma is a malignancy of plasma cells initiated and driven by primary and secondary genetic events. However, myeloma plasma cell survival and proliferation might be sustained by non-genetic drivers. Z-DNA-binding protein 1 (ZBP1; also known as DAI) is an interferon-inducible, Z-nucleic ac...

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Detalles Bibliográficos
Autores principales: Ponnusamy, Kanagaraju, Tzioni, Maria Myrsini, Begum, Murshida, Robinson, Mark E., Caputo, Valentina S., Katsarou, Alexia, Trasanidis, Nikolaos, Xiao, Xiaolin, Kostopoulos, Ioannis V., Iskander, Deena, Roberts, Irene, Trivedi, Pritesh, Auner, Holger W., Naresh, Kikkeri, Chaidos, Aristeidis, Karadimitris, Anastasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883568/
https://www.ncbi.nlm.nih.gov/pubmed/33596642
http://dx.doi.org/10.3324/haematol.2020.274480

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