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Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia

Symptomatic methotrexate-related central neurotoxicity (MTX neurotoxicity) is a severe toxicity experienced during acute lymphoblastic leukemia (ALL) therapy with potential long-term neurologic complications. Risk factors and long-term outcomes require further study. We conducted a systematic, retro...

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Detalles Bibliográficos
Autores principales:	Mateos, Marion K., Marshall, Glenn M, Barbaro, Pasquale M., Quinn, Michael C.J., George, Carly, Mayoh, Chelsea, Sutton, Rosemary, Revesz, Tamas, Giles, Jodie E, Barbaric, Draga, Alvaro, Frank, Mechinaud, Françoise, Catchpoole, Daniel, Lawson, John A., Chenevix-Trench, Georgia, MacGregor, Stuart, S.Kotecha, Rishi, Dalla-Pozza, Luciano, Trahair, Toby N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883571/ https://www.ncbi.nlm.nih.gov/pubmed/33567813 http://dx.doi.org/10.3324/haematol.2020.268565

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