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Overexpression of MUC1 Induces Non-Canonical TGF-β Signaling in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human cancers. Transforming Growth Factor Beta (TGF-β) is a cytokine that switches from a tumor-suppressor at early stages to a tumor promoter in the late stages of tumor development, by yet unknown mechanisms. Tumor associated MUC1 is...

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Detalles Bibliográficos
Autores principales: Bose, Mukulika, Grover, Priyanka, Sanders, Alexa J., Zhou, Ru, Ahmad, Mohammad, Shwartz, Sophia, Lala, Priyanka, Nath, Sritama, Yazdanifar, Mahboubeh, Brouwer, Cory, Mukherjee, Pinku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883581/
https://www.ncbi.nlm.nih.gov/pubmed/35237602
http://dx.doi.org/10.3389/fcell.2022.821875

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