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Scalable Dual-Fluorescence Assay for Functional Interpretation of HNF-4α Missense Variants

AIM: The study aimed to develop a scalable dual-fluorescence assay in cells to enable the functional interpretation of HNF-4α missense variants identified in exome sequencing, which can be used to guide clinical diagnosis. METHODS: Using mOrange2 and GFP fluorescence proteins to track the expression...

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Detalles Bibliográficos
Autores principales:	Guo, Yiming, Zhao, Jing, Huang, Rong, Xu, Tao, Zhou, Kaixin, Zheng, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883583/ https://www.ncbi.nlm.nih.gov/pubmed/35237236 http://dx.doi.org/10.3389/fendo.2022.812747

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