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How to stain nucleic acids and proteins in Miller spreads

The spreading technique proposed by Miller and Beatty in 1969 allowed for the first time the visualization at transmission electron microscopy of nucleic acids and chromatin in an isolated and distended conformation. This approach is beneficial since it can reveal many aspects of chromatin organizat...

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Detalles Bibliográficos
Autores principales: Zannino, Lorena, Biggiogera, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883610/
https://www.ncbi.nlm.nih.gov/pubmed/35212500
http://dx.doi.org/10.4081/ejh.2022.3364