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LAP2α preserves genome integrity through assisting RPA deposition on damaged chromatin

BACKGROUND: Single-stranded DNA (ssDNA) coated with replication protein A (RPA) acts as a key platform for the recruitment and exchange of genome maintenance factors in DNA damage response. Yet, how the formation of the ssDNA-RPA intermediate is regulated remains elusive. RESULTS: Here, we report th...

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Detalles Bibliográficos
Autores principales:	Bao, Kaiwen, Zhang, Qi, Liu, Shuai, Song, Nan, Guo, Qiushi, Liu, Ling, Tian, Shanshan, Hao, Jihui, Zhu, Yi, Zhang, Kai, Ai, Ding, Yang, Jie, Yao, Zhi, Foisner, Roland, Shi, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883701/ https://www.ncbi.nlm.nih.gov/pubmed/35227284 http://dx.doi.org/10.1186/s13059-022-02638-6

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