Suppressing fatty acid synthase by type I interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2

SARS-CoV-2 is an emerging viral pathogen and a major global public health challenge since December of 2019, with limited effective treatments throughout the pandemic. As part of the innate immune response to viral infection, type I interferons (IFN-I) trigger a signaling cascade that culminates in t...

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Detalles Bibliográficos
Autores principales: Aliyari, Saba R., Ghaffari, Amir Ali, Pernet, Olivier, Parvatiyar, Kislay, Wang, Yao, Gerami, Hoda, Tong, Ann-Jay, Vergnes, Laurent, Takallou, Armin, Zhang, Adel, Wei, Xiaochao, Chilin, Linda D., Wu, Yuntao, Semenkovich, Clay F., Reue, Karen, Smale, Stephen T., Lee, Benhur, Cheng, Genhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883762/
https://www.ncbi.nlm.nih.gov/pubmed/35251918
http://dx.doi.org/10.1016/j.apsb.2022.02.019

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