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A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis

Background: Multiple studies have investigated the correlations of mortality, mechanical ventilation, and intensive care unit (ICU) admissions with CAC scores. This analysis overviews the prognostic capability of CAC scoring in mortality, mechanical ventilation, and ICU admission for hospitalized CO...

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Autores principales: Lee, Kevin Kyungmin, Rahimi, Osman, Lee, Charlie Kyungchan, Shafi, Amaan, Hawwass, Dalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883990/
https://www.ncbi.nlm.nih.gov/pubmed/35225939
http://dx.doi.org/10.3390/medsci10010005
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author Lee, Kevin Kyungmin
Rahimi, Osman
Lee, Charlie Kyungchan
Shafi, Amaan
Hawwass, Dalia
author_facet Lee, Kevin Kyungmin
Rahimi, Osman
Lee, Charlie Kyungchan
Shafi, Amaan
Hawwass, Dalia
author_sort Lee, Kevin Kyungmin
collection PubMed
description Background: Multiple studies have investigated the correlations of mortality, mechanical ventilation, and intensive care unit (ICU) admissions with CAC scores. This analysis overviews the prognostic capability of CAC scoring in mortality, mechanical ventilation, and ICU admission for hospitalized COVID-19 patients. Methods: Online search was conducted on PubMed, Cochrane Library, and Scopus from inception to 22 November 2021 to identify studies involving CAC scores in relation to ICU admission, mechanical ventilation, and death rates. Results: A total of eight studies were analyzed. In the absence of CAC group compared with the presence of CAC score, there was an increase in mortality in the presence of CAC (RR 2.24, 95% CI, 1.41–3.56; p < 0.001). In the low CAC group and high CAC group, high CAC group had increase in mortality (RR 2.74; 95% CI, 1.94–3.86; p < 0.00001). There was no statistical difference in outcomes of mechanical ventilation and ICU admission between any of the groups. Conclusion: This meta-analysis strictly examined the outcomes of interest in death, mechanical ventilation, and ICU admission while comparing the CAC scores in patients with COVID-19. Given these findings, CAC scoring can aid in stratifying patients, thus allowing earlier interventions in rapidly developing illnesses.
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spelling pubmed-88839902022-03-01 A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis Lee, Kevin Kyungmin Rahimi, Osman Lee, Charlie Kyungchan Shafi, Amaan Hawwass, Dalia Med Sci (Basel) Systematic Review Background: Multiple studies have investigated the correlations of mortality, mechanical ventilation, and intensive care unit (ICU) admissions with CAC scores. This analysis overviews the prognostic capability of CAC scoring in mortality, mechanical ventilation, and ICU admission for hospitalized COVID-19 patients. Methods: Online search was conducted on PubMed, Cochrane Library, and Scopus from inception to 22 November 2021 to identify studies involving CAC scores in relation to ICU admission, mechanical ventilation, and death rates. Results: A total of eight studies were analyzed. In the absence of CAC group compared with the presence of CAC score, there was an increase in mortality in the presence of CAC (RR 2.24, 95% CI, 1.41–3.56; p < 0.001). In the low CAC group and high CAC group, high CAC group had increase in mortality (RR 2.74; 95% CI, 1.94–3.86; p < 0.00001). There was no statistical difference in outcomes of mechanical ventilation and ICU admission between any of the groups. Conclusion: This meta-analysis strictly examined the outcomes of interest in death, mechanical ventilation, and ICU admission while comparing the CAC scores in patients with COVID-19. Given these findings, CAC scoring can aid in stratifying patients, thus allowing earlier interventions in rapidly developing illnesses. MDPI 2022-01-21 /pmc/articles/PMC8883990/ /pubmed/35225939 http://dx.doi.org/10.3390/medsci10010005 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Lee, Kevin Kyungmin
Rahimi, Osman
Lee, Charlie Kyungchan
Shafi, Amaan
Hawwass, Dalia
A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis
title A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis
title_full A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis
title_fullStr A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis
title_full_unstemmed A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis
title_short A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis
title_sort meta-analysis: coronary artery calcium score and covid-19 prognosis
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883990/
https://www.ncbi.nlm.nih.gov/pubmed/35225939
http://dx.doi.org/10.3390/medsci10010005
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