An In Vivo Fluorescence Resonance Energy Transfer-Based Imaging Platform for Targeted Drug Discovery and Cancer Therapy

In the present study, an efficient in vivo drug screening platform is established based on FRET technique. We transfected cancer cells with FRET-based caspase-3 (C3) sensor and validated the cell lines by detecting the change in FRET signal caused by the in vitro drug-induced cell apoptosis. Further...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Fuqiang, Ai, Nana, Huang, Shigao, Jiang, Cheng, Mughal, Muhammad Jameel, Ge, Wei, Wang, Guanyu, Deng, Chu-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884137/
https://www.ncbi.nlm.nih.gov/pubmed/35237583
http://dx.doi.org/10.3389/fbioe.2022.839078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884137/
https://www.ncbi.nlm.nih.gov/pubmed/35237583
http://dx.doi.org/10.3389/fbioe.2022.839078

Ejemplares similares