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Data Augmentation and Transfer Learning for Data Quality Assessment in Respiratory Monitoring

Changes in respiratory rate have been found to be one of the early signs of health deterioration in patients. In remote environments where diagnostic tools and medical attention are scarce, such as deep space exploration, the monitoring of the respiratory signal becomes crucial to timely detect life...

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Autores principales: Rozo, Andrea, Moeyersons, Jonathan, Morales, John, Garcia van der Westen, Roberto, Lijnen, Lien, Smeets, Christophe, Jantzen, Sjors, Monpellier, Valerie, Ruttens, David, Van Hoof, Chris, Van Huffel, Sabine, Groenendaal, Willemijn, Varon, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884147/
https://www.ncbi.nlm.nih.gov/pubmed/35237576
http://dx.doi.org/10.3389/fbioe.2022.806761
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author Rozo, Andrea
Moeyersons, Jonathan
Morales, John
Garcia van der Westen, Roberto
Lijnen, Lien
Smeets, Christophe
Jantzen, Sjors
Monpellier, Valerie
Ruttens, David
Van Hoof, Chris
Van Huffel, Sabine
Groenendaal, Willemijn
Varon, Carolina
author_facet Rozo, Andrea
Moeyersons, Jonathan
Morales, John
Garcia van der Westen, Roberto
Lijnen, Lien
Smeets, Christophe
Jantzen, Sjors
Monpellier, Valerie
Ruttens, David
Van Hoof, Chris
Van Huffel, Sabine
Groenendaal, Willemijn
Varon, Carolina
author_sort Rozo, Andrea
collection PubMed
description Changes in respiratory rate have been found to be one of the early signs of health deterioration in patients. In remote environments where diagnostic tools and medical attention are scarce, such as deep space exploration, the monitoring of the respiratory signal becomes crucial to timely detect life-threatening conditions. Nowadays, this signal can be measured using wearable technology; however, the use of such technology is often hampered by the low quality of the recordings, which leads more often to wrong diagnosis and conclusions. Therefore, to apply these data in diagnosis analysis, it is important to determine which parts of the signal are of sufficient quality. In this context, this study aims to evaluate the performance of a signal quality assessment framework, where two machine learning algorithms (support vector machine–SVM, and convolutional neural network–CNN) were used. The models were pre-trained using data of patients suffering from chronic obstructive pulmonary disease. The generalization capability of the models was evaluated by testing them on data from a different patient population, presenting normal and pathological breathing. The new patients underwent bariatric surgery and performed a controlled breathing protocol, displaying six different breathing patterns. Data augmentation (DA) and transfer learning (TL) were used to increase the size of the training set and to optimize the models for the new dataset. The effect of the different breathing patterns on the performance of the classifiers was also studied. The SVM did not improve when using DA, however, when using TL, the performance improved significantly (p < 0.05) compared to DA. The opposite effect was observed for CNN, where the biggest improvement was obtained using DA, while TL did not show a significant change. The models presented a low performance for shallow, slow and fast breathing patterns. These results suggest that it is possible to classify respiratory signals obtained with wearable technologies using pre-trained machine learning models. This will allow focusing on the relevant data and avoid misleading conclusions because of the noise, when designing bio-monitoring systems.
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spelling pubmed-88841472022-03-01 Data Augmentation and Transfer Learning for Data Quality Assessment in Respiratory Monitoring Rozo, Andrea Moeyersons, Jonathan Morales, John Garcia van der Westen, Roberto Lijnen, Lien Smeets, Christophe Jantzen, Sjors Monpellier, Valerie Ruttens, David Van Hoof, Chris Van Huffel, Sabine Groenendaal, Willemijn Varon, Carolina Front Bioeng Biotechnol Bioengineering and Biotechnology Changes in respiratory rate have been found to be one of the early signs of health deterioration in patients. In remote environments where diagnostic tools and medical attention are scarce, such as deep space exploration, the monitoring of the respiratory signal becomes crucial to timely detect life-threatening conditions. Nowadays, this signal can be measured using wearable technology; however, the use of such technology is often hampered by the low quality of the recordings, which leads more often to wrong diagnosis and conclusions. Therefore, to apply these data in diagnosis analysis, it is important to determine which parts of the signal are of sufficient quality. In this context, this study aims to evaluate the performance of a signal quality assessment framework, where two machine learning algorithms (support vector machine–SVM, and convolutional neural network–CNN) were used. The models were pre-trained using data of patients suffering from chronic obstructive pulmonary disease. The generalization capability of the models was evaluated by testing them on data from a different patient population, presenting normal and pathological breathing. The new patients underwent bariatric surgery and performed a controlled breathing protocol, displaying six different breathing patterns. Data augmentation (DA) and transfer learning (TL) were used to increase the size of the training set and to optimize the models for the new dataset. The effect of the different breathing patterns on the performance of the classifiers was also studied. The SVM did not improve when using DA, however, when using TL, the performance improved significantly (p < 0.05) compared to DA. The opposite effect was observed for CNN, where the biggest improvement was obtained using DA, while TL did not show a significant change. The models presented a low performance for shallow, slow and fast breathing patterns. These results suggest that it is possible to classify respiratory signals obtained with wearable technologies using pre-trained machine learning models. This will allow focusing on the relevant data and avoid misleading conclusions because of the noise, when designing bio-monitoring systems. Frontiers Media S.A. 2022-02-14 /pmc/articles/PMC8884147/ /pubmed/35237576 http://dx.doi.org/10.3389/fbioe.2022.806761 Text en Copyright © 2022 Rozo, Moeyersons, Morales, Garcia van der Westen, Lijnen, Smeets, Jantzen, Monpellier, Ruttens, Van Hoof, Van Huffel, Groenendaal and Varon. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Rozo, Andrea
Moeyersons, Jonathan
Morales, John
Garcia van der Westen, Roberto
Lijnen, Lien
Smeets, Christophe
Jantzen, Sjors
Monpellier, Valerie
Ruttens, David
Van Hoof, Chris
Van Huffel, Sabine
Groenendaal, Willemijn
Varon, Carolina
Data Augmentation and Transfer Learning for Data Quality Assessment in Respiratory Monitoring
title Data Augmentation and Transfer Learning for Data Quality Assessment in Respiratory Monitoring
title_full Data Augmentation and Transfer Learning for Data Quality Assessment in Respiratory Monitoring
title_fullStr Data Augmentation and Transfer Learning for Data Quality Assessment in Respiratory Monitoring
title_full_unstemmed Data Augmentation and Transfer Learning for Data Quality Assessment in Respiratory Monitoring
title_short Data Augmentation and Transfer Learning for Data Quality Assessment in Respiratory Monitoring
title_sort data augmentation and transfer learning for data quality assessment in respiratory monitoring
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884147/
https://www.ncbi.nlm.nih.gov/pubmed/35237576
http://dx.doi.org/10.3389/fbioe.2022.806761
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