The Molecular Pathways of Pyroptosis in Atherosclerosis

Atherosclerosis (AS) is a chronic inflammatory disease seriously endangering human health, whose occurrence and development is related to many factors. Pyroptosis is a recently identified novel programmed cell death associated with an inflammatory response and involved in the formation and progressi...

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Detalles Bibliográficos
Autores principales: Song, Dan, Li, Manman, Yu, Xue, Wang, Yuqin, Fan, Jiaying, Yang, Wei, Yang, Liming, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884404/
https://www.ncbi.nlm.nih.gov/pubmed/35237603
http://dx.doi.org/10.3389/fcell.2022.824165
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author Song, Dan
Li, Manman
Yu, Xue
Wang, Yuqin
Fan, Jiaying
Yang, Wei
Yang, Liming
Li, Hong
author_facet Song, Dan
Li, Manman
Yu, Xue
Wang, Yuqin
Fan, Jiaying
Yang, Wei
Yang, Liming
Li, Hong
author_sort Song, Dan
collection PubMed
description Atherosclerosis (AS) is a chronic inflammatory disease seriously endangering human health, whose occurrence and development is related to many factors. Pyroptosis is a recently identified novel programmed cell death associated with an inflammatory response and involved in the formation and progression of AS by activating different signaling pathways. Protein modifications of the sirtuin family and microRNAs (miRNAs) can directly or indirectly affect pyroptosis-related molecules. It is important to link atherosclerosis, thermogenesis and molecular modifications. This article will systematically review the molecular pathways of pyroptosis in AS, which can provide a new perspective for AS prevention and treatment.
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spelling pubmed-88844042022-03-01 The Molecular Pathways of Pyroptosis in Atherosclerosis Song, Dan Li, Manman Yu, Xue Wang, Yuqin Fan, Jiaying Yang, Wei Yang, Liming Li, Hong Front Cell Dev Biol Cell and Developmental Biology Atherosclerosis (AS) is a chronic inflammatory disease seriously endangering human health, whose occurrence and development is related to many factors. Pyroptosis is a recently identified novel programmed cell death associated with an inflammatory response and involved in the formation and progression of AS by activating different signaling pathways. Protein modifications of the sirtuin family and microRNAs (miRNAs) can directly or indirectly affect pyroptosis-related molecules. It is important to link atherosclerosis, thermogenesis and molecular modifications. This article will systematically review the molecular pathways of pyroptosis in AS, which can provide a new perspective for AS prevention and treatment. Frontiers Media S.A. 2022-02-14 /pmc/articles/PMC8884404/ /pubmed/35237603 http://dx.doi.org/10.3389/fcell.2022.824165 Text en Copyright © 2022 Song, Li, Yu, Wang, Fan, Yang, Yang and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Song, Dan
Li, Manman
Yu, Xue
Wang, Yuqin
Fan, Jiaying
Yang, Wei
Yang, Liming
Li, Hong
The Molecular Pathways of Pyroptosis in Atherosclerosis
title The Molecular Pathways of Pyroptosis in Atherosclerosis
title_full The Molecular Pathways of Pyroptosis in Atherosclerosis
title_fullStr The Molecular Pathways of Pyroptosis in Atherosclerosis
title_full_unstemmed The Molecular Pathways of Pyroptosis in Atherosclerosis
title_short The Molecular Pathways of Pyroptosis in Atherosclerosis
title_sort molecular pathways of pyroptosis in atherosclerosis
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884404/
https://www.ncbi.nlm.nih.gov/pubmed/35237603
http://dx.doi.org/10.3389/fcell.2022.824165
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