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Euglycemic Diabetic Ketoacidosis in a Pregnant Woman With Severe COVID-19: A Case Report

Euglycemic diabetic ketoacidosis (DKA) of pregnancy is an uncommon but serious condition that poses a substantial risk to the fetus. The physiological state of pregnancy itself predisposes women to ketosis and ketoacidosis, which can be further exacerbated by acute stressors such as infection. In th...

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Autores principales: Harman, Megan L, Cuellar, Emery M, Burkhart Denora, Allyson R, Pokhriyal, Megha, Mussarat, Saad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884461/
https://www.ncbi.nlm.nih.gov/pubmed/35242454
http://dx.doi.org/10.7759/cureus.21649
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author Harman, Megan L
Cuellar, Emery M
Burkhart Denora, Allyson R
Pokhriyal, Megha
Mussarat, Saad
author_facet Harman, Megan L
Cuellar, Emery M
Burkhart Denora, Allyson R
Pokhriyal, Megha
Mussarat, Saad
author_sort Harman, Megan L
collection PubMed
description Euglycemic diabetic ketoacidosis (DKA) of pregnancy is an uncommon but serious condition that poses a substantial risk to the fetus. The physiological state of pregnancy itself predisposes women to ketosis and ketoacidosis, which can be further exacerbated by acute stressors such as infection. In this article, we describe a case of a pregnant woman with gestational diabetes and coronavirus disease 2019 (COVID-19) requiring mechanical ventilation who developed euglycemic DKA during her hospital course. Despite treating the patient with standard DKA protocol, fetal heart monitoring was non-reassuring and, hence, a cesarean section was performed. Postoperatively, her DKA resolved; however, she was maintained on supportive ventilation for continued management of her severe COVID-19 infection. In light of the ongoing pandemic, it is essential that healthcare teams closely monitor pregnant women presenting with COVID-19 infection for early signs of euglycemic DKA so that treatment may be initiated early and feto-maternal complications are avoided.
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spelling pubmed-88844612022-03-02 Euglycemic Diabetic Ketoacidosis in a Pregnant Woman With Severe COVID-19: A Case Report Harman, Megan L Cuellar, Emery M Burkhart Denora, Allyson R Pokhriyal, Megha Mussarat, Saad Cureus Endocrinology/Diabetes/Metabolism Euglycemic diabetic ketoacidosis (DKA) of pregnancy is an uncommon but serious condition that poses a substantial risk to the fetus. The physiological state of pregnancy itself predisposes women to ketosis and ketoacidosis, which can be further exacerbated by acute stressors such as infection. In this article, we describe a case of a pregnant woman with gestational diabetes and coronavirus disease 2019 (COVID-19) requiring mechanical ventilation who developed euglycemic DKA during her hospital course. Despite treating the patient with standard DKA protocol, fetal heart monitoring was non-reassuring and, hence, a cesarean section was performed. Postoperatively, her DKA resolved; however, she was maintained on supportive ventilation for continued management of her severe COVID-19 infection. In light of the ongoing pandemic, it is essential that healthcare teams closely monitor pregnant women presenting with COVID-19 infection for early signs of euglycemic DKA so that treatment may be initiated early and feto-maternal complications are avoided. Cureus 2022-01-26 /pmc/articles/PMC8884461/ /pubmed/35242454 http://dx.doi.org/10.7759/cureus.21649 Text en Copyright © 2022, Harman et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Harman, Megan L
Cuellar, Emery M
Burkhart Denora, Allyson R
Pokhriyal, Megha
Mussarat, Saad
Euglycemic Diabetic Ketoacidosis in a Pregnant Woman With Severe COVID-19: A Case Report
title Euglycemic Diabetic Ketoacidosis in a Pregnant Woman With Severe COVID-19: A Case Report
title_full Euglycemic Diabetic Ketoacidosis in a Pregnant Woman With Severe COVID-19: A Case Report
title_fullStr Euglycemic Diabetic Ketoacidosis in a Pregnant Woman With Severe COVID-19: A Case Report
title_full_unstemmed Euglycemic Diabetic Ketoacidosis in a Pregnant Woman With Severe COVID-19: A Case Report
title_short Euglycemic Diabetic Ketoacidosis in a Pregnant Woman With Severe COVID-19: A Case Report
title_sort euglycemic diabetic ketoacidosis in a pregnant woman with severe covid-19: a case report
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884461/
https://www.ncbi.nlm.nih.gov/pubmed/35242454
http://dx.doi.org/10.7759/cureus.21649
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