ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of nonapoptotic phosphatidylserine

Cancer metastasis is the cause of the majority of cancer-related deaths. In this study, we demonstrated that no expression or low expression of ATP11B in conjunction with high expression of PTDSS2, which was negatively regulated by BRCA1, markedly accelerates tumor metastasis. Further analysis revea...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Su, Sek Man, Zhang, Xin, Chan, Un In, Adhav, Ragini, Shu, Xiaodong, Liu, Jianlin, Li, Jianjie, Mo, Lihua, Wang, Yuqing, An, Tingting, Lei, Josh Haipeng, Miao, Kai, Deng, Chu-Xia, Xu, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884903/
https://www.ncbi.nlm.nih.gov/pubmed/35025764
http://dx.doi.org/10.1172/JCI149473

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