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Therapeutic targets for cardiac fibrosis: from old school to next-gen

Cardiovascular diseases remain the leading cause of death worldwide, with pathological fibrotic remodeling mediated by activated cardiac myofibroblasts representing a unifying theme across etiologies. Despite the profound contributions of myocardial fibrosis to cardiac dysfunction and heart failure,...

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Detalles Bibliográficos
Autores principales: Travers, Joshua G., Tharp, Charles A., Rubino, Marcello, McKinsey, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884906/
https://www.ncbi.nlm.nih.gov/pubmed/35229727
http://dx.doi.org/10.1172/JCI148554