SIRPγ-expressing cancer stem-like cells promote immune escape of lung cancer via Hippo signaling

Cancer stem-like cells (CSLCs) acquire enhanced immune checkpoint responses to evade immune cell killing and promote tumor progression. Here we showed that signal regulatory protein γ (SIRPγ) determined CSLC properties and immune evasiveness in a small population of lung adenocarcinoma (LUAD) cancer...

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Detalles Bibliográficos
Autores principales: Xu, Chuan, Jin, Guoxiang, Wu, Hong, Cui, Wei, Wang, Yu-Hui, Manne, Rajesh Kumar, Wang, Guihua, Zhang, Weina, Zhang, Xian, Han, Fei, Cai, Zhen, Pan, Bo-Syong, Hsu, Che-Chia, Liu, Yiqiang, Zhang, Anmei, Long, Jie, Zou, Hongbo, Wang, Shuang, Ma, Xiaodan, Duan, Jinling, Wang, Bin, Liu, Weihui, Lan, Haitao, Xiong, Qing, Xue, Gang, Chen, Zhongzhu, Xu, Zhigang, Furth, Mark E., Haigh Molina, Sarah, Lu, Yong, Xie, Dan, Bian, Xiu-Wu, Lin, Hui-Kuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884909/
https://www.ncbi.nlm.nih.gov/pubmed/35229723
http://dx.doi.org/10.1172/JCI141797

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