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PARP Inhibitor Applicability: Detailed Assays for Homologous Recombination Repair Pathway Components

Poly(ADP-ribose) polymerase inhibitors (PARPi) have been in clinical use since 2014 for certain patients with germline BRCA1/2 mutations, but as evidence and approvals for their use in a wider range of patients grow, the question of how best to identify patients who would benefit from PARPi becomes...

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Detalles Bibliográficos
Autores principales:	O’Sullivan Coyne, Geraldine, Karlovich, Chris, Wilsker, Deborah, Voth, Andrea Regier, Parchment, Ralph E, Chen, Alice P, Doroshow, James H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885121/ https://www.ncbi.nlm.nih.gov/pubmed/35237050 http://dx.doi.org/10.2147/OTT.S278092

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