Ferritinophagy-Mediated Ferroptosis and Activation of Keap1/Nrf2/HO-1 Pathway Were Conducive to EMT Inhibition of Gastric Cancer Cells in Action of 2,2′-Di-pyridineketone Hydrazone Dithiocarbamate Butyric Acid Ester

In metastasis of cancer cells, the epithelial-mesenchymal transition (EMT) is prerequired. Ferroptosis is an iron-mediated cellular death process, but whether it involves EMT regulation remains elusive. In addition, how stress responders (Nrf2) respond to the redox alteration and cross-talking betwe...

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Detalles Bibliográficos
Autores principales: Guan, Deng, Zhou, Wei, Wei, Huiping, Wang, Ting, Zheng, Kangwei, Yang, Chunjie, Feng, Rui, Xu, Ruifang, Fu, Yun, Li, Cuiping, Li, Yongli, Li, Changzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885181/
https://www.ncbi.nlm.nih.gov/pubmed/35237380
http://dx.doi.org/10.1155/2022/3920664

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