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Visual Corneal Photomechanical Analysis Is Combined with the Pentacam Correlation Index for the Diagnosis of Cone Corneas at Different Stages of Progression

Cone-shaped corneas are blinding eye diseases characterised by dilated and thinning corneal tissue and forward conical protrusions, most often in adolescents. Early detection and intervention can prevent further dilatation of the cornea. The prevailing examination methods and techniques are not diff...

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Autores principales: Cheng, Qiong, Zhang, Feng, Tian, Tixian, Wu, Lan, Li, Linna, Chen, Meixia, Zhou, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885271/
https://www.ncbi.nlm.nih.gov/pubmed/35237391
http://dx.doi.org/10.1155/2022/4682901
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author Cheng, Qiong
Zhang, Feng
Tian, Tixian
Wu, Lan
Li, Linna
Chen, Meixia
Zhou, Ye
author_facet Cheng, Qiong
Zhang, Feng
Tian, Tixian
Wu, Lan
Li, Linna
Chen, Meixia
Zhou, Ye
author_sort Cheng, Qiong
collection PubMed
description Cone-shaped corneas are blinding eye diseases characterised by dilated and thinning corneal tissue and forward conical protrusions, most often in adolescents. Early detection and intervention can prevent further dilatation of the cornea. The prevailing examination methods and techniques are not difficult to diagnose clinical cone corneas, but there are limitations in the diagnosis of early cone corneas (static cone corneas and subclinical cone corneas). In this study, we investigated the diagnostic value of the combination of these two instruments in the diagnosis of clinical cone corneas and subclinical cone corneas by performing the Pentacam and Corvis ST examinations in healthy eyes and dystrophic cone corneas. This study provides a theoretical basis for early cone cornea screening and diagnosis. The analysis revealed that only TP, SPA1, ARTh, and bIOP were normally distributed among all included parameters, and only bIOP was normally distributed with equal variance. TBI and CBI indices have a certain sensitivity and specificity for the diagnosis of subclinical cone corneas, with a strong diagnostic ability, and can be used for screening and early diagnosis of cone corneas.
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spelling pubmed-88852712022-03-01 Visual Corneal Photomechanical Analysis Is Combined with the Pentacam Correlation Index for the Diagnosis of Cone Corneas at Different Stages of Progression Cheng, Qiong Zhang, Feng Tian, Tixian Wu, Lan Li, Linna Chen, Meixia Zhou, Ye J Healthc Eng Research Article Cone-shaped corneas are blinding eye diseases characterised by dilated and thinning corneal tissue and forward conical protrusions, most often in adolescents. Early detection and intervention can prevent further dilatation of the cornea. The prevailing examination methods and techniques are not difficult to diagnose clinical cone corneas, but there are limitations in the diagnosis of early cone corneas (static cone corneas and subclinical cone corneas). In this study, we investigated the diagnostic value of the combination of these two instruments in the diagnosis of clinical cone corneas and subclinical cone corneas by performing the Pentacam and Corvis ST examinations in healthy eyes and dystrophic cone corneas. This study provides a theoretical basis for early cone cornea screening and diagnosis. The analysis revealed that only TP, SPA1, ARTh, and bIOP were normally distributed among all included parameters, and only bIOP was normally distributed with equal variance. TBI and CBI indices have a certain sensitivity and specificity for the diagnosis of subclinical cone corneas, with a strong diagnostic ability, and can be used for screening and early diagnosis of cone corneas. Hindawi 2022-02-21 /pmc/articles/PMC8885271/ /pubmed/35237391 http://dx.doi.org/10.1155/2022/4682901 Text en Copyright © 2022 Qiong Cheng et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Cheng, Qiong
Zhang, Feng
Tian, Tixian
Wu, Lan
Li, Linna
Chen, Meixia
Zhou, Ye
Visual Corneal Photomechanical Analysis Is Combined with the Pentacam Correlation Index for the Diagnosis of Cone Corneas at Different Stages of Progression
title Visual Corneal Photomechanical Analysis Is Combined with the Pentacam Correlation Index for the Diagnosis of Cone Corneas at Different Stages of Progression
title_full Visual Corneal Photomechanical Analysis Is Combined with the Pentacam Correlation Index for the Diagnosis of Cone Corneas at Different Stages of Progression
title_fullStr Visual Corneal Photomechanical Analysis Is Combined with the Pentacam Correlation Index for the Diagnosis of Cone Corneas at Different Stages of Progression
title_full_unstemmed Visual Corneal Photomechanical Analysis Is Combined with the Pentacam Correlation Index for the Diagnosis of Cone Corneas at Different Stages of Progression
title_short Visual Corneal Photomechanical Analysis Is Combined with the Pentacam Correlation Index for the Diagnosis of Cone Corneas at Different Stages of Progression
title_sort visual corneal photomechanical analysis is combined with the pentacam correlation index for the diagnosis of cone corneas at different stages of progression
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885271/
https://www.ncbi.nlm.nih.gov/pubmed/35237391
http://dx.doi.org/10.1155/2022/4682901
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