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Impaired phosphocreatine metabolism in white adipocytes promotes inflammation

The mechanisms promoting disturbed white adipocyte function in obesity remain largely unclear. Herein, we integrate white adipose tissue (WAT) metabolomic and transcriptomic data from clinical cohorts and find that the WAT phosphocreatine/creatine ratio is increased and creatine kinase-B expression...

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Detalles Bibliográficos
Autores principales:	Maqdasy, Salwan, Lecoutre, Simon, Renzi, Gianluca, Frendo-Cumbo, Scott, Rizo-Roca, David, Moritz, Thomas, Juvany, Marta, Hodek, Ondrej, Gao, Hui, Couchet, Morgane, Witting, Michael, Kerr, Alastair, Bergo, Martin O., Choudhury, Robin P., Aouadi, Myriam, Zierath, Juleen R., Krook, Anna, Mejhert, Niklas, Rydén, Mikael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885409/ https://www.ncbi.nlm.nih.gov/pubmed/35165448 http://dx.doi.org/10.1038/s42255-022-00525-9

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