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Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants
Vaccine hesitancy and emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) escaping vaccine-induced immune responses highlight the urgency for new COVID-19 therapeutics. Engineered angiotensin-converting enzyme 2 (ACE2) proteins with augmented binding...
Autores principales: | Zhang, Lianghui, Dutta, Soumajit, Xiong, Shiqin, Chan, Matthew, Chan, Kui K., Fan, Timothy M., Bailey, Keith L., Lindeblad, Matthew, Cooper, Laura M., Rong, Lijun, Gugliuzza, Anthony F., Shukla, Diwakar, Procko, Erik, Rehman, Jalees, Malik, Asrar B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885411/ https://www.ncbi.nlm.nih.gov/pubmed/35046611 http://dx.doi.org/10.1038/s41589-021-00965-6 |
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