Comparative systeomics to elucidate physiological differences between CHO and SP2/0 cell lines

Omics-based tools were coupled with bioinformatics for a systeomics analysis of two biopharma cell types: Chinese hamster ovary (M-CHO and CHO-K1) and SP2/0. Exponential and stationary phase samples revealed more than 10,000 transcripts and 6000 proteins across these two manufacturing cell lines. A...

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Detalles Bibliográficos
Autores principales: Demirhan, Deniz, Kumar, Amit, Zhu, Jie, Poulsen, Pi Camilla, Majewska, Natalia I., Sebastian, Yinong, Chaerkady, Raghothama, Yu, Wen, Zhu, Wei, Zhuang, Li, Shah, Punit, Lekstrom, Kristen, Cole, Robert N., Zhang, Hui, Betenbaugh, Michael J., Bowen, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885639/
https://www.ncbi.nlm.nih.gov/pubmed/35228567
http://dx.doi.org/10.1038/s41598-022-06886-1

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