Cargando…
Neuronal–glial communication perturbations in murine SOD1(G93A) spinal cord
Amyotrophic lateral sclerosis (ALS) is an incurable disease characterized by proteinaceous aggregate accumulation and neuroinflammation culminating in rapidly progressive lower and upper motor neuron death. To interrogate cell-intrinsic and inter-cell type perturbations in ALS, single-nucleus RNA se...
Autores principales: | MacLean, Michael, López-Díez, Raquel, Vasquez, Carolina, Gugger, Paul F., Schmidt, Ann Marie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885678/ https://www.ncbi.nlm.nih.gov/pubmed/35228715 http://dx.doi.org/10.1038/s42003-022-03128-y |
Ejemplares similares
-
Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1(G93A) murine model of amyotrophic lateral sclerosis in a sex-dependent manner
por: MacLean, Michael, et al.
Publicado: (2021) -
Human Glial-Restricted Progenitor Transplantation into Cervical Spinal Cord of the SOD1(G93A) Mouse Model of ALS
por: Lepore, Angelo C., et al.
Publicado: (2011) -
Gamisoyo-San Ameliorates Neuroinflammation in the Spinal Cord of hSOD1(G93A) Transgenic Mice
por: Cai, MuDan, et al.
Publicado: (2018) -
Cu(II)(atsm) improves the neurological phenotype and survival of SOD1(G93A) mice and selectively increases enzymatically active SOD1 in the spinal cord
por: Hilton, James B., et al.
Publicado: (2017) -
Preliminary Observation about Alteration of Proteins and Their Potential Functions in Spinal Cord of SOD1 G93A Transgenic Mice
por: Zhang, Jie, et al.
Publicado: (2018)