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Single-cell gene fusion detection by scFusion

Gene fusions can play important roles in tumor initiation and progression. While fusion detection so far has been from bulk samples, full-length single-cell RNA sequencing (scRNA-seq) offers the possibility of detecting gene fusions at the single-cell level. However, scRNA-seq data have a high noise...

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Detalles Bibliográficos
Autores principales: Jin, Zijie, Huang, Wenjian, Shen, Ning, Li, Juan, Wang, Xiaochen, Dong, Jiqiao, Park, Peter J., Xi, Ruibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885711/
https://www.ncbi.nlm.nih.gov/pubmed/35228538
http://dx.doi.org/10.1038/s41467-022-28661-6

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