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Myoglobin promotes macrophage polarization to M1 type and pyroptosis via the RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI

Crush syndrome (CS) is a life-threatening illness in traffic accidents and earthquakes. Crush syndrome-induced acute kidney injury (CS-AKI) is considered to be mainly due to myoglobin (Mb) circulation and deposition after skeletal muscle ruptures and releases. Macrophages are the primary immune cell...

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Detalles Bibliográficos
Autores principales:	Li, Ning, Chen, Jiale, Geng, Chenhao, Wang, Xinyue, Wang, Yuru, Sun, Na, Wang, Pengtao, Han, Lu, Li, Zizheng, Fan, Haojun, Hou, Shike, Gong, Yanhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885737/ https://www.ncbi.nlm.nih.gov/pubmed/35228524 http://dx.doi.org/10.1038/s41420-022-00894-w

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