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Inhibition of spleen tyrosine kinase decreases donor specific antibody levels in a rat model of sensitization

Antibody mediated rejection is a major cause of renal allograft loss. Circulating preformed donor specific antibodies (DSA) can result as a consequence of blood transfusion, pregnancy or prior transplantation. Current treatment strategies are limited due to partial or transient efficacy, adverse sid...

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Detalles Bibliográficos
Autores principales:	Tempest-Roe, Shenzhen, Prendecki, Maria, McAdoo, Stephen P., Clarke, Candice, Tanna, Anisha, Turner-Stokes, Tabitha, Masuda, Esteban S., Willicombe, Michelle, Cook, H. Terence, Roufosse, Candice, Taube, David, Pusey, Charles D., Tam, Frederick W. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885754/ https://www.ncbi.nlm.nih.gov/pubmed/35228550 http://dx.doi.org/10.1038/s41598-022-06413-2

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