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Tumor RNA transfected DCs derived from iPS cells elicit cytotoxicity against cancer cells induced from colorectal cancer patients in vitro

Significant efficacy of induced pluripotent stem cells (iPSCs) in generating DCs for cancer vaccine therapy was suggested in our previous studies. In clinical application of DC vaccine therapy, however, few DC vaccine systems have shown strong clinical response. To enhance immunogenicity in the DC v...

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Detalles Bibliográficos
Autores principales: Maruoka, Shimpei, Ojima, Toshiyasu, Iwamoto, Hiromitsu, Kitadani, Junya, Tabata, Hirotaka, Tominaga, Shinta, Katsuda, Masahiro, Hayata, Keiji, Takeuchi, Akihiro, Yamaue, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885822/
https://www.ncbi.nlm.nih.gov/pubmed/35228610
http://dx.doi.org/10.1038/s41598-022-07305-1