Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation

Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) encodes the 4EBP1 protein, a negative regulator of mRNA translation and a substrate of the mechanistic target of rapamycin (mTOR), whose function and relevance in cancer is still under debate. Here, we analyzed EIF4EBP1 express...

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Detalles Bibliográficos
Autores principales: Hauffe, Laura, Picard, Daniel, Musa, Julian, Remke, Marc, Grünewald, Thomas G. P., Rotblat, Barak, Reifenberger, Guido, Leprivier, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885828/
https://www.ncbi.nlm.nih.gov/pubmed/35228525
http://dx.doi.org/10.1038/s41420-022-00883-z

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