Targeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is a lethal cardiovascular disease, and there is no proven drug treatment for this condition. In this study, by using the Connectivity Map (CMap) approach, we explored naringenin, a naturally occurring citrus flavonoid, as a putative agent for inhibiting AAA. We then...

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Detalles Bibliográficos
Autores principales: Jia, Yiting, Zhang, Lu, Liu, Ziyi, Mao, Chenfeng, Ma, Zihan, Li, Wenqiang, Yu, Fang, Wang, Yingbao, Huang, Yaqian, Zhang, Weizhen, Zheng, Jingang, Wang, Xian, Xu, Qingbo, Zhang, Jian, Feng, Wei, Yun, Caihong, Liu, Chuanju, Sun, Jinpeng, Fu, Yi, Cui, Qinghua, Kong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885854/
https://www.ncbi.nlm.nih.gov/pubmed/35228523
http://dx.doi.org/10.1038/s41421-021-00363-1

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