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The impact of remote home monitoring of people with COVID-19 using pulse oximetry: A national population and observational study

BACKGROUND: Remote home monitoring of people testing positive for COVID-19 using pulse oximetry was implemented across England during the Winter of 2020/21 to identify falling blood oxygen saturation levels at an early stage. This was hypothesised to enable earlier hospital admission, reduce the nee...

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Autores principales: Sherlaw-Johnson, Chris, Georghiou, Theo, Morris, Steve, Crellin, Nadia E., Litchfield, Ian, Massou, Efthalia, Sidhu, Manbinder S., Tomini, Sonila M., Vindrola-Padros, Cecilia, Walton, Holly, Fulop, Naomi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886180/
https://www.ncbi.nlm.nih.gov/pubmed/35252824
http://dx.doi.org/10.1016/j.eclinm.2022.101318
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author Sherlaw-Johnson, Chris
Georghiou, Theo
Morris, Steve
Crellin, Nadia E.
Litchfield, Ian
Massou, Efthalia
Sidhu, Manbinder S.
Tomini, Sonila M.
Vindrola-Padros, Cecilia
Walton, Holly
Fulop, Naomi J.
author_facet Sherlaw-Johnson, Chris
Georghiou, Theo
Morris, Steve
Crellin, Nadia E.
Litchfield, Ian
Massou, Efthalia
Sidhu, Manbinder S.
Tomini, Sonila M.
Vindrola-Padros, Cecilia
Walton, Holly
Fulop, Naomi J.
author_sort Sherlaw-Johnson, Chris
collection PubMed
description BACKGROUND: Remote home monitoring of people testing positive for COVID-19 using pulse oximetry was implemented across England during the Winter of 2020/21 to identify falling blood oxygen saturation levels at an early stage. This was hypothesised to enable earlier hospital admission, reduce the need for intensive care and improve survival. This study is an evaluation of the clinical effectiveness of the pre-hospital monitoring programme, COVID oximetry @home (CO@h). METHODS: The setting was all Clinical Commissioning Group (CCG) areas in England where there were complete data on the number of people enrolled onto the programme between 2nd November 2020 and 21st February 2021. We analysed relationships at a geographical area level between the extent to which people aged 65 or over were enrolled onto the programme and outcomes over the period between November 2020 to February 2021. FINDINGS: For every 10% increase in coverage of the programme, mortality was reduced by 2% (95% confidence interval:4% reduction to 1% increase), admissions increased by 3% (-1% to 7%), in-hospital mortality fell by 3% (-8% to 3%) and lengths of stay increased by 1·8% (-1·2% to 4·9%). None of these results are statistically significant, although the confidence interval indicates that any adverse effect on mortality would be small, but a mortality reduction of up to 4% may have resulted from the programme. INTERPRETATION: There are several possible explanations for our findings. One is that CO@h did not have the hypothesised impact. Another is that the low rates of enrolment and incomplete data in many areas reduced the chances of detecting any impact that may have existed. Also, CO@h has been implemented in many different ways across the country and these may have had varying levels of effect. FUNDING: This is independent research funded by the National Institute for Health Research, Health Services & Delivery Research programme (RSET Project no. 16/138/17; BRACE Project no. 16/138/31) and NHSEI. NJF is an NIHR Senior Investigator.
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spelling pubmed-88861802022-03-01 The impact of remote home monitoring of people with COVID-19 using pulse oximetry: A national population and observational study Sherlaw-Johnson, Chris Georghiou, Theo Morris, Steve Crellin, Nadia E. Litchfield, Ian Massou, Efthalia Sidhu, Manbinder S. Tomini, Sonila M. Vindrola-Padros, Cecilia Walton, Holly Fulop, Naomi J. eClinicalMedicine Articles BACKGROUND: Remote home monitoring of people testing positive for COVID-19 using pulse oximetry was implemented across England during the Winter of 2020/21 to identify falling blood oxygen saturation levels at an early stage. This was hypothesised to enable earlier hospital admission, reduce the need for intensive care and improve survival. This study is an evaluation of the clinical effectiveness of the pre-hospital monitoring programme, COVID oximetry @home (CO@h). METHODS: The setting was all Clinical Commissioning Group (CCG) areas in England where there were complete data on the number of people enrolled onto the programme between 2nd November 2020 and 21st February 2021. We analysed relationships at a geographical area level between the extent to which people aged 65 or over were enrolled onto the programme and outcomes over the period between November 2020 to February 2021. FINDINGS: For every 10% increase in coverage of the programme, mortality was reduced by 2% (95% confidence interval:4% reduction to 1% increase), admissions increased by 3% (-1% to 7%), in-hospital mortality fell by 3% (-8% to 3%) and lengths of stay increased by 1·8% (-1·2% to 4·9%). None of these results are statistically significant, although the confidence interval indicates that any adverse effect on mortality would be small, but a mortality reduction of up to 4% may have resulted from the programme. INTERPRETATION: There are several possible explanations for our findings. One is that CO@h did not have the hypothesised impact. Another is that the low rates of enrolment and incomplete data in many areas reduced the chances of detecting any impact that may have existed. Also, CO@h has been implemented in many different ways across the country and these may have had varying levels of effect. FUNDING: This is independent research funded by the National Institute for Health Research, Health Services & Delivery Research programme (RSET Project no. 16/138/17; BRACE Project no. 16/138/31) and NHSEI. NJF is an NIHR Senior Investigator. Elsevier 2022-03-01 /pmc/articles/PMC8886180/ /pubmed/35252824 http://dx.doi.org/10.1016/j.eclinm.2022.101318 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Articles
Sherlaw-Johnson, Chris
Georghiou, Theo
Morris, Steve
Crellin, Nadia E.
Litchfield, Ian
Massou, Efthalia
Sidhu, Manbinder S.
Tomini, Sonila M.
Vindrola-Padros, Cecilia
Walton, Holly
Fulop, Naomi J.
The impact of remote home monitoring of people with COVID-19 using pulse oximetry: A national population and observational study
title The impact of remote home monitoring of people with COVID-19 using pulse oximetry: A national population and observational study
title_full The impact of remote home monitoring of people with COVID-19 using pulse oximetry: A national population and observational study
title_fullStr The impact of remote home monitoring of people with COVID-19 using pulse oximetry: A national population and observational study
title_full_unstemmed The impact of remote home monitoring of people with COVID-19 using pulse oximetry: A national population and observational study
title_short The impact of remote home monitoring of people with COVID-19 using pulse oximetry: A national population and observational study
title_sort impact of remote home monitoring of people with covid-19 using pulse oximetry: a national population and observational study
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886180/
https://www.ncbi.nlm.nih.gov/pubmed/35252824
http://dx.doi.org/10.1016/j.eclinm.2022.101318
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