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JAK2V617F-Positive Endothelial Cells Induce Apoptosis and Release JAK2V617F-Positive Microparticles

OBJECTIVE: Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) have a high propensity for thrombosis, which has been attributed to increased blood counts, endothelial cell (EC) dysfunction, and inflammation. The presence of the JAK2V617F mutation in the ECs of MPN patients has been...

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Detalles Bibliográficos
Autores principales: Hekimoğlu, Hilal, Toprak, Selin Fulya, Sözer, Selçuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886274/
https://www.ncbi.nlm.nih.gov/pubmed/34981912
http://dx.doi.org/10.4274/tjh.galenos.2021.2021.0607