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Single‐cell transcriptomics uncovers an instructive T‐cell receptor role in adult γδ T‐cell lineage commitment

After entering the adult thymus, bipotent T‐cell progenitors give rise to αβ or γδ T cells. To determine whether the γδ T‐cell receptor (TCR) has an instructive role in γδ T‐cell lineage commitment or only “confirms” a pre‐established γδ Τ‐cell lineage state, we exploited mice lacking expression of...

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Detalles Bibliográficos
Autores principales:	Scaramuzzino, Sara, Potier, Delphine, Ordioni, Robin, Grenot, Pierre, Payet‐Bornet, Dominique, Luche, Hervé, Malissen, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886544/ https://www.ncbi.nlm.nih.gov/pubmed/35128689 http://dx.doi.org/10.15252/embj.2021110023

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