Cargando…

Genetic Analysis of TB Susceptibility Variants in Ghana Reveals Candidate Protective Loci in SORBS2 and SCL11A1 Genes

Despite advancements made toward diagnostics, tuberculosis caused by Mycobacterium africanum (Maf) and Mycobacterium tuberculosis sensu stricto (Mtbss) remains a major public health issue. Human host factors are key players in tuberculosis (TB) outcomes and treatment. Research is required to probe t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asante-Poku, Adwoa, Morgan, Portia, Osei-Wusu, Stephen, Aboagye, Samuel Yaw, Asare, Prince, Otchere, Isaac Darko, Adadey, Samuel Mawuli, Mnika, Khuthala, Esoh, Kevin, Mawuta, Kenneth Hayibor, Arthur, Nelly, Forson, Audrey, Mazandu, Gaston Kuzamunu, Wonkam, Ambroise, Yeboah-Manu, Dorothy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886735/ https://www.ncbi.nlm.nih.gov/pubmed/35242163 http://dx.doi.org/10.3389/fgene.2021.729737

Ejemplares similares

Predictors of Adverse TB Treatment Outcome among TB/HIV Patients Compared with Non-HIV Patients in the Greater Accra Regional Hospital from 2008 to 2016
por: Hayibor, Kenneth Mawuta, et al.
Publicado: (2020)

The Hearing Impairment Ontology: A Tool for Unifying Hearing Impairment Knowledge to Enhance Collaborative Research
por: Hotchkiss, Jade, et al.
Publicado: (2019)

Molecular epidemiology of Mycobacterium tuberculosis complex in the Volta Region of Ghana
por: Ameke, Selassie, et al.
Publicado: (2021)

Enhancing Genetic Medicine: Rapid and Cost-Effective Molecular Diagnosis for a GJB2 Founder Mutation for Hearing Impairment in Ghana
por: M. Adadey, Samuel, et al.
Publicado: (2020)

Age Estimate of GJB2-p.(Arg143Trp) Founder Variant in Hearing Impairment in Ghana, Suggests Multiple Independent Origins across Populations
por: Aboagye, Elvis Twumasi, et al.
Publicado: (2022)

Hearing loss in Africa: current genetic profile
por: Adadey, Samuel Mawuli, et al.
Publicado: (2021)

Clinical characteristics and risk factors of relative systemic hypertension and hypertension among sickle cell patients in Cameroon
por: Nguweneza, Arthemon, et al.
Publicado: (2022)

The Relevance of Genomic Epidemiology for Control of Tuberculosis in West Africa
por: Asare, Prince, et al.
Publicado: (2021)

Global Distribution of Founder Variants Associated with Non-Syndromic Hearing Impairment
por: Aboagye, Elvis Twumasi, et al.
Publicado: (2023)

Cell-based analysis of CLIC5A and SLC12A2 variants associated with hearing impairment in two African families
por: Adadey, Samuel Mawuli, et al.
Publicado: (2022)

GJB2 and GJB6 Mutations in Non-Syndromic Childhood Hearing Impairment in Ghana
por: Adadey, Samuel M., et al.
Publicado: (2019)

Hydroxyurea-Induced miRNA Expression in Sickle Cell Disease Patients in Africa
por: Mnika, Khuthala, et al.
Publicado: (2019)

Second-line anti-tuberculosis drug resistance testing in Ghana identifies the first extensively drug-resistant tuberculosis case
por: Osei-Wusu, Stephen, et al.
Publicado: (2018)

TB-diabetes co-morbidity in Ghana: The importance of Mycobacterium africanum infection
por: Asante-Poku, Adwoa, et al.
Publicado: (2019)

A novel autosomal dominant GREB1L variant associated with non-syndromic hearing impairment in Ghana
por: Adadey, Samuel Mawuli, et al.
Publicado: (2022)

A molecular and epidemiological study of Vibrio cholerae isolates from cholera outbreaks in southern Ghana
por: Danso, Emelia Konadu, et al.
Publicado: (2020)

Reduced transmission of Mycobacterium africanum compared to Mycobacterium tuberculosis in urban West Africa
por: Asare, Prince, et al.
Publicado: (2018)

Connexin Genes Variants Associated with Non-Syndromic Hearing Impairment: A Systematic Review of the Global Burden
por: Adadey, Samuel Mawuli, et al.
Publicado: (2020)

Analysis of drug resistance among difficult-to-treat tuberculosis patients in Ghana identifies several pre-XDR TB cases
por: Otchere, Isaac Darko, et al.
Publicado: (2023)

Spatio-Temporal Distribution of Mycobacterium tuberculosis Complex Strains in Ghana
por: Yeboah-Manu, Dorothy, et al.
Publicado: (2016)

GJB2 and GJB6 Mutations in Hereditary Recessive Non-Syndromic Hearing Impairment in Cameroon
por: Tingang Wonkam, Edmond, et al.
Publicado: (2019)

Molecular epidemiology and whole genome sequencing analysis of clinical Mycobacterium bovis from Ghana
por: Otchere, Isaac Darko, et al.
Publicado: (2019)

Investigations of Kidney Dysfunction-Related Gene Variants in Sickle Cell Disease Patients in Cameroon (Sub-Saharan Africa)
por: Ngo-Bitoungui, Valentina J., et al.
Publicado: (2021)

Knowledge and Challenges Associated With Hearing Impairment in Affected Individuals From Cameroon (Sub-Saharan Africa)
por: Wonkam-Tingang, Edmond, et al.
Publicado: (2021)

Genotypic and phenotypic diversity of Mycobacterium tuberculosis complex genotypes prevalent in West Africa
por: Osei-Wusu, Stephen, et al.
Publicado: (2021)

Evolutionary history of sickle-cell mutation: implications for global genetic medicine
por: Esoh, Kevin, et al.
Publicado: (2021)

5613165 INVESTIGATING VARIANTS ASSOCIATED WITH QUANTITATIVE RED BLOOD CELL PHENOTYPES FROM TOPMED PREDICTIONS IN AFRICAN SICKLE CELL DISEASE POPULATIONS.
por: Samie, N., et al.
Publicado: (2023)

A monoallelic variant in EYA1 is associated with Branchio‐Otic syndrome in a Malian family
por: Yalcouyé, Abdoulaye, et al.
Publicado: (2022)

Whole Genome Sequencing and Spatial Analysis Identifies Recent Tuberculosis Transmission Hotspots in Ghana
por: Asare, Prince, et al.
Publicado: (2020)

Bi-Allelic Novel Variants in CLIC5 Identified in a Cameroonian Multiplex Family with Non-Syndromic Hearing Impairment
por: Wonkam-Tingang, Edmond, et al.
Publicado: (2020)

Skills Capacity Building For Health Care Services and Research Through the Sickle Pan African Research Consortium
por: Nnodu, Obiageli Eunice, et al.
Publicado: (2022)

Editorial: Building capacity for sickle cell disease research and healthcare
por: Nembaware, Victoria, et al.
Publicado: (2023)

Further confirmation of the association of SLC12A2 with non-syndromic autosomal-dominant hearing impairment
por: Adadey, Samuel M., et al.
Publicado: (2021)

Detection and characterization of drug-resistant conferring genes in Mycobacterium tuberculosis complex strains: A prospective study in two distant regions of Ghana
por: Otchere, I.D., et al.
Publicado: (2016)

Genomic epidemiological analysis identifies high relapse among individuals with recurring tuberculosis and provides evidence of recent household-related transmission of tuberculosis in Ghana
por: Asare, Prince, et al.
Publicado: (2021)

Molecular epidemiology of Mycobacterium africanum in Ghana
por: Asante-Poku, Adwoa, et al.
Publicado: (2016)

Current profile of Charcot‐Marie‐Tooth disease in Africa: A systematic review
por: Yalcouyé, Abdoulaye, et al.
Publicado: (2022)

Mycobacterium africanum Is Associated with Patient Ethnicity in Ghana
por: Asante-Poku, Adwoa, et al.
Publicado: (2015)

Genetic modifiers of long‐term survival in sickle cell anemia
por: Wonkam, Ambroise, et al.
Publicado: (2020)

5593300 INVESTIGATIONS OF KIDNEY DYSFUNCTION-RELATED GENE VARIANTS IN SICKLE CELL DISEASE PATIENTS IN CAMEROON (SUB-SAHARAN AFRICA)
por: NGO BITOUNGUI, V.B., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f6jntc99aq0r0d2n933o203339