DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors

BACKGROUND: Pancreatic neuroendocrine neoplasms (PanNENs) fall into two subclasses: the well-differentiated, low- to high-grade pancreatic neuroendocrine tumors (PanNETs), and the poorly-differentiated, high-grade pancreatic neuroendocrine carcinomas (PanNECs). While recent studies suggest an endocr...

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Detalles Bibliográficos
Autores principales: Simon, Tincy, Riemer, Pamela, Jarosch, Armin, Detjen, Katharina, Di Domenico, Annunziata, Bormann, Felix, Menne, Andrea, Khouja, Slim, Monjé, Nanna, Childs, Liam H., Lenze, Dido, Leser, Ulf, Rossner, Florian, Morkel, Markus, Blüthgen, Nils, Pavel, Marianne, Horst, David, Capper, David, Marinoni, Ilaria, Perren, Aurel, Mamlouk, Soulafa, Sers, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886788/
https://www.ncbi.nlm.nih.gov/pubmed/35227293
http://dx.doi.org/10.1186/s13073-022-01018-w

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