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The mitospecific domain of Mrp7 (bL27) supports mitochondrial translation during fermentation and is required for effective adaptation to respiration

We demonstrate here that mitoribosomal protein synthesis, responsible for the synthesis of oxidative phosphorylation (OXPHOS) subunits encoded by the mitochondrial genome, occurs at high levels during glycolysis fermentation and in a manner uncoupled from OXPHOS complex assembly regulation. Furtherm...

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Detalles Bibliográficos
Autores principales: Anderson, Jessica M., Box, Jodie M., Stuart, Rosemary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886811/
https://www.ncbi.nlm.nih.gov/pubmed/34731012
http://dx.doi.org/10.1091/mbc.E21-07-0370