Cargando…

Dynamics of intracellular neonatal Fc receptor–ligand interactions in primary macrophages using biophysical fluorescence techniques

The neonatal Fc receptor (FcRn) is responsible for the recycling of endocytosed albumin and IgG, and contributes to their long plasma half-life. We recently identified an FcRn-dependent recycling pathway from macropinosomes in macrophages; however, little is known about the dynamics of intracellular...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pannek, Andreas, Houghton, Fiona J., Verhagen, Anne M., Dower, Steven K., Hinde, Elizabeth, Gleeson, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886815/ https://www.ncbi.nlm.nih.gov/pubmed/34731029 http://dx.doi.org/10.1091/mbc.E21-02-0061

Ejemplares similares

The endosomal system of primary human vascular endothelial cells and albumin–FcRn trafficking
por: Pannek, Andreas, et al.
Publicado: (2023)

Ligand Valency Affects Transcytosis, Recycling and Intracellular Trafficking Mediated by the Neonatal Fc Receptor
por: Tesar, Devin B, et al.
Publicado: (2006)

Half-life–extended recombinant coagulation factor IX–albumin fusion protein is recycled via the FcRn-mediated pathway
por: Chia, Jenny, et al.
Publicado: (2018)

Transport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomes
Publicado: (1986)

Arf5-mediated regulation of mTORC1 at the plasma membrane
por: Makhoul, Christian, et al.
Publicado: (2023)

Highly sensitive HPLC analysis and biophysical characterization of N‐glycans of IgG‐Fc domain in comparison between CHO and 293 cells using FcγRIIIa ligand
por: Kosuge, Hirofumi, et al.
Publicado: (2020)

Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis
por: Challa, Dilip K., et al.
Publicado: (2019)

The neonatal Fc receptor expression during macrophage differentiation is related to autophagy
por: Lamamy, Juliette, et al.
Publicado: (2022)

THE INTRACELLULAR LOCALIZATION OF HEME BY A FLUORESCENCE TECHNIQUE
por: Granick, S., et al.
Publicado: (1965)

The Neonatal Fc Receptor (FcRn): A Misnomer?
por: Pyzik, Michal, et al.
Publicado: (2019)

The neonatal Fc receptor in cancer FcRn in cancer
por: Cadena Castaneda, Diana, et al.
Publicado: (2020)

Advanced Techniques in Biophysics
por: Arrondo, José Luis R, et al.
Publicado: (2006)

Biophysical Evaluation of Rhesus Macaque Fc Gamma Receptors Reveals Similar IgG Fc Glycoform Preferences to Human Receptors
por: Crowley, Andrew R., et al.
Publicado: (2021)

Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life
por: Gjølberg, Torleif Tollefsrud, et al.
Publicado: (2022)

Biophysical Characterization of the Contribution of the Fab Region to the IgG-FcγRIIIa Interaction
por: Kosuge, Hirofumi, et al.
Publicado: (2022)

Biophysical thermodynamics of intracellular processes: molecular machines of the living cell
por: Blumenfeld, Lev A, et al.
Publicado: (1994)

Biophysical characterization of chloride intracellular channel 6 (CLIC6)
por: Loyo-Celis, Veronica, et al.
Publicado: (2023)

The therapeutic age of the neonatal Fc receptor
por: Pyzik, Michal, et al.
Publicado: (2023)

G-Quadruplexes and Their Ligands: Biophysical Methods to Unravel G-Quadruplex/Ligand Interactions
por: Santos, Tiago, et al.
Publicado: (2021)

Characterization of the Rabbit Neonatal Fc Receptor (FcRn) and Analyzing the Immunophenotype of the Transgenic Rabbits That Overexpresses FcRn
por: Catunda Lemos, Ana Paula, et al.
Publicado: (2012)

Profiling the Biophysical Developability Properties of Common IgG1 Fc Effector Silencing Variants
por: Pejchal, Robert, et al.
Publicado: (2023)

Making connections — strategies for single molecule fluorescence biophysics
por: Grohmann, Dina, et al.
Publicado: (2013)

Surveillance for Intracellular Antibody by Cytosolic Fc Receptor TRIM21
por: McEwan, William A.
Publicado: (2016)

Advanced Microscopy Techniques for Molecular Biophysics
por: Barsanti, Laura, et al.
Publicado: (2023)

Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2
por: Casella, Bianca Maria, et al.
Publicado: (2023)

Neonatal Fc Receptor: From Immunity to Therapeutics
por: Kuo, Timothy T., et al.
Publicado: (2010)

The neonatal Fc receptor is expressed by human lymphocytes
por: van Bilsen, K, et al.
Publicado: (2010)

Neonatal Fc Receptor–Targeted Therapies in Neurology
por: Nelke, Christopher, et al.
Publicado: (2022)

Rapid redistribution of clathrin onto macrophage plasma membranes in response to Fc receptor-ligand interaction during frustrated phagocytosis
Publicado: (1986)

A novel role for the Fc receptor gamma subunit: enhancement of Fc gamma R ligand affinity
Publicado: (1996)

In vivo fluorescence lifetime imaging of macrophage intracellular metabolism during wound responses in zebrafish
por: Miskolci, Veronika, et al.
Publicado: (2022)

Antibody Fc engineering for enhanced neonatal Fc receptor binding and prolonged circulation half-life
por: Mackness, Brian C., et al.
Publicado: (2019)

Abundant Intracellular IgG in Enterocytes and Endoderm Lacking FcRn
por: Mohanty, Sudhasri, et al.
Publicado: (2013)

Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21
por: Dickson, Claire, et al.
Publicado: (2018)

Analysis of the HTLV-1 Gag assembly pathway by biophysical fluorescence
por: Fogarty, Keir H, et al.
Publicado: (2011)

Analysis of biophysical and functional consequences of tropomyosin–fluorescent protein fusions
por: Brooker, Holly R., et al.
Publicado: (2016)

Ultrafast Fluorescence Spectroscopy via Upconversion and Its Applications in Biophysics
por: Cao, Simin, et al.
Publicado: (2021)

Applications of biophysical techniques in drug discovery and development
por: Verbić, Tatjana Ž.
Publicado: (2019)

Application of Biophysical Techniques to Cellular and Molecular Oncology
por: Lidke, Diane S., et al.
Publicado: (2023)

Selection of Nanobodies that Target Human Neonatal Fc Receptor
por: Andersen, Jan Terje, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_drhklka3jj0a610digk8n2fva6