The microtubule- and PP1-binding activities of Drosophila melanogaster Spc105 control the kinetics of SAC satisfaction

KNL1 is a large intrinsically disordered kinetochore (KT) protein that recruits spindle assembly checkpoint (SAC) components to mediate SAC signaling. The N-terminal region (NTR) of KNL1 possesses two activities that have been implicated in SAC silencing: microtubule (MT) binding and protein phospha...

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Detalles Bibliográficos
Autores principales: Audett, Margaux R., Johnson, Erin L., McGory, Jessica M., Barcelos, Dylan M., Szalai, Evelin Oroszne, Przewloka, Marcin R., Maresca, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886820/
https://www.ncbi.nlm.nih.gov/pubmed/34705493
http://dx.doi.org/10.1091/mbc.E21-06-0307-T

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