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PSnpBind: a database of mutated binding site protein–ligand complexes constructed using a multithreaded virtual screening workflow
A key concept in drug design is how natural variants, especially the ones occurring in the binding site of drug targets, affect the inter-individual drug response and efficacy by altering binding affinity. These effects have been studied on very limited and small datasets while, ideally, a large dat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886843/ https://www.ncbi.nlm.nih.gov/pubmed/35227289 http://dx.doi.org/10.1186/s13321-021-00573-5 |