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High throughput single-cell genome sequencing gives insights into the generation and evolution of mosaic aneuploidy in Leishmania donovani

Leishmania, a unicellular eukaryotic parasite, is a unique model for aneuploidy and cellular heterogeneity, along with their potential role in adaptation to environmental stresses. Somy variation within clonal populations was previously explored in a small subset of chromosomes using fluorescence hy...

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Detalles Bibliográficos
Autores principales: Negreira, Gabriel H, Monsieurs, Pieter, Imamura, Hideo, Maes, Ilse, Kuk, Nada, Yagoubat, Akila, Van den Broeck, Frederik, Sterkers, Yvon, Dujardin, Jean-Claude, Domagalska, Malgorzata A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886908/
https://www.ncbi.nlm.nih.gov/pubmed/34893872
http://dx.doi.org/10.1093/nar/gkab1203