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Type I interferon responsive microglia shape cortical development and behavior

Microglia are brain resident phagocytes that can engulf synaptic components and extracellular matrix as well as whole neurons. However, whether there are unique molecular mechanisms that regulate these distinct phagocytic states is unknown. Here we define a molecularly distinct microglial subset who...

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Detalles Bibliográficos
Autores principales: Escoubas, Caroline C., Dorman, Leah C., Nguyen, Phi T., Lagares-Linares, Christian, Nakajo, Haruna, Anderson, Sarah R., Cuevas, Beatriz, Vainchtein, Ilia D., Silva, Nicholas J., Xiao, Yinghong, Lidsky, Peter V., Wang, Ellen Y., Taloma, Sunrae E., Nakao-Inoue, Hiromi, Schwer, Bjoern, Andino, Raul, Nowakowski, Tomasz J., Molofsky, Anna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887080/
https://www.ncbi.nlm.nih.gov/pubmed/35233577
http://dx.doi.org/10.1101/2021.04.29.441889