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Reduction in Plasmodium falciparum Pfk13 and pfg377 allele diversity through time in southern Vietnam

BACKGROUND: Plasmodium falciparum has acquired resistance to artemisinin in Southeast Asia, with mutations in the P. falciparum Kelch-13 (Pfk13) gene associated with the resistance phenotype. The widespread use of Artemisinin-based combination therapy (ACT)s in Southeast Asia has led to the selectio...

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Detalles Bibliográficos
Autores principales: Thieu, Nguyen Quang, Chinh, Vu Duc, Van Hanh, Truong, Van Dung, Nguyen, Takagi, Hidekazu, Annoura, Takeshi, Kawai, Satoru, Masuda, Gaku, Van Tuan, Nguyen, Hung, Vu Viet, Nakazawa, Shusuke, Culleton, Richard, Binh, Nguyen Thi Huong, Maeno, Yoshimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887123/
https://www.ncbi.nlm.nih.gov/pubmed/35232492
http://dx.doi.org/10.1186/s41182-022-00409-4