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Reduction in Plasmodium falciparum Pfk13 and pfg377 allele diversity through time in southern Vietnam
BACKGROUND: Plasmodium falciparum has acquired resistance to artemisinin in Southeast Asia, with mutations in the P. falciparum Kelch-13 (Pfk13) gene associated with the resistance phenotype. The widespread use of Artemisinin-based combination therapy (ACT)s in Southeast Asia has led to the selectio...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887123/ https://www.ncbi.nlm.nih.gov/pubmed/35232492 http://dx.doi.org/10.1186/s41182-022-00409-4 |