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RBBP6 activates the pre-mRNA 3′ end processing machinery in humans

3′ end processing of most human mRNAs is carried out by the cleavage and polyadenylation specificity factor (CPSF; CPF in yeast). Endonucleolytic cleavage of the nascent pre-mRNA defines the 3′ end of the mature transcript, which is important for mRNA localization, translation, and stability. Cleava...

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Detalles Bibliográficos
Autores principales:	Boreikaite, Vytaute, Elliott, Thomas S., Chin, Jason W., Passmore, Lori A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887125/ https://www.ncbi.nlm.nih.gov/pubmed/35177536 http://dx.doi.org/10.1101/gad.349223.121

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