Structural insights into the non-inhibitory mechanism of the anti-EGFR EgB4 nanobody

BACKGROUND: The epidermal growth factor receptor (EGFR) is involved in various developmental processes, and alterations of its extracellular segment are associated with several types of cancers, in particular glioblastoma multiforme (GBM). The EGFR extracellular region is therefore a primary target...

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Detalles Bibliográficos
Autores principales: Zeronian, Matthieu R., Doulkeridou, Sofia, van Bergen en Henegouwen, Paul M. P., Janssen, Bert J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887186/
https://www.ncbi.nlm.nih.gov/pubmed/35232398
http://dx.doi.org/10.1186/s12860-022-00412-x

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