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CRISPRroots: on- and off-target assessment of RNA-seq data in CRISPR–Cas9 edited cells
The CRISPR-Cas9 genome editing tool is used to study genomic variants and gene knockouts, and can be combined with transcriptomic analyses to measure the effects of such alterations on gene expression. But how can one be sure that differential gene expression is due to a successful intended edit and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887420/ https://www.ncbi.nlm.nih.gov/pubmed/34850137 http://dx.doi.org/10.1093/nar/gkab1131 |