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Physical ARTEMIS:DNA-PKcs interaction is necessary for V(D)J recombination
The nuclease ARTEMIS and the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are involved in the repair of physiological and pathogenic DNA double strand breaks. Both proteins are indispensable for the hairpin-opening activity in V(D)J recombination and therefore essential for the adaptive...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887466/ https://www.ncbi.nlm.nih.gov/pubmed/35150269 http://dx.doi.org/10.1093/nar/gkac071 |