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Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation

Histone 3 lysine 4 trimethylation (H3K4me3) is an epigenetic mark found at gene promoters and CpG islands. H3K4me3 is essential for mammalian development, yet mechanisms underlying its genomic targeting are poorly understood. H3K4me3 methyltransferases SETD1B and MLL2 (KMT2B) are essential for oogen...

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Detalles Bibliográficos
Autores principales:	Hanna, Courtney W, Huang, Jiahao, Belton, Christian, Reinhardt, Susanne, Dahl, Andreas, Andrews, Simon, Stewart, A Francis, Kranz, Andrea, Kelsey, Gavin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887468/ https://www.ncbi.nlm.nih.gov/pubmed/35137160 http://dx.doi.org/10.1093/nar/gkac051

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