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Nuclear export restricts Gdown1 to a mitotic function

Approximately half of purified mammalian RNA polymerase II (Pol II) is associated with a tightly interacting sub-stoichiometric subunit, Gdown1. Previous studies have established that Gdown1 inhibits transcription initiation through competitive interactions with general transcription factors and blo...

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Detalles Bibliográficos
Autores principales: Ball, Christopher B, Parida, Mrutyunjaya, Santana, Juan F, Spector, Benjamin M, Suarez, Gustavo A, Price, David H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887472/
https://www.ncbi.nlm.nih.gov/pubmed/35048979
http://dx.doi.org/10.1093/nar/gkac015